Molecular dynamics simulations of d(C-G-C-G-A) X d(T-C-G-C-G) with and without "hydrated" counterions.
نویسندگان
چکیده
منابع مشابه
Vaccination .B. C. G
This article was presented by the author at the Vaccination Seminar of May 26, 1972, National University Medical School.
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The deoxynucleotide fragment d(GpGpCpCpGpGpCpC) was synthesized and crystallized, and its three-dimensional structure was determined by x-ray diffraction techniques to a resolution of 2.25 A. The molecule forms a right-handed double helix in which the two base pairs at either end of the molecule are in the conventional A-DNA conformation, while the central four base pairs have a modified form i...
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Background & Objective: Host resistance to Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. IL-18 known as interferon-γ inducing factor, stimulate IFN-γ production by T-cells. According to the important role of IL-18 in defense against VL and known effect of IL-18 gene polymorphisms on its production, the aim of this study was ...
متن کاملThe structure of B-helical C-G-A-T-C-G-A-T-C-G and comparison with C-C-A-A-C-G-T-T-G-G. The effect of base pair reversals.
The crystal structure of the DNA decamer C-G-A-T-C-G-A-T-C-G has been solved to a resolution of 1.5 A, with a final R-factor of 16.1% for 5,107 two-sigma reflections. Crystals are orthorhombic space group P2(1)2(1)2(1), with cell dimensions a = 38.93 A, b = 39.63 A, c = 33.30 A, and 10 base pairs/asymmetric unit. The final structure contains 404 DNA atoms, 142 water molecules treated as oxygen ...
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م?نک?م هئرا ار هتفا?م?معت یاهیژولوپوت برضلصاح ف?رعت ادتبا هماننا?اپ ن?ا رد و برضلصاح ن?ب یهطبار و هتخادرپ برضلصاح ن?ا صاوخ ?خرب نا?ب هب نآ زا سپ یدنبمه م?هافم ?سررب هب سپس .م?نک?م ?سررب ار هتفا?م?معت یژولوپوت یاهرگلمع یارب فنوخ?ت یه?ضق هک م?هد?م ناشن ?عون هب .م?زادرپ?م هتفا?م?معت ?گدرشف و .تسا رارقرب ز?ن هتفا?م?معت یاهیژولوپوت
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1985
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.82.3.755